Cyclic Dinucleotides
2',3'-cGAMP
Quick view. A mixed-linkage cyclic GMP-AMP research compound containing one 2'-5' and one 3'-5' phosphodiester linkage. CAS 1441190-66-4. Catalog target purity: 99.95%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2',3'-cGAMP is classified as cyclic dinucleotides (Formula C20H24N10O13P2; molecular weight 674.40).
2',3'-cGAMP — Mixed-linkage cyclic-dinucleotide research
For 2',3'-cGAMP, activity can depend on linkage stereochemistry, receptor variant, cell entry, salt form and assay format; molar calculations should use the exact supplied form.
Names and search terms
Confirmed or normalized name variants
- 2'-3'-cyclic GMP-AMP
- c[G(2',5')pA(3',5')p]
Useful catalog search terms
- 1441190-66-4
Physicochemical data
| PubChem CID | 136313972 |
|---|---|
| Linkage | One 2'-5' and one 3'-5' phosphodiester linkage |
| Product form | Free-acid representation |
| Storage temperature | -20 C, sealed and protected from moisture |
| InChI | InChI=1S/C20H24N10O13P2/c21-14-8-15(24-3-23-14)29(4-25-8)18-11(32)12-7(41-18)2-39-45(36,37)43-13-10(31)6(1-38-44(34,35)42-12)40-19(13)30-5-26-9-16(30)27-20(22)28-17(9)33/h3-7,10-13,18-19,31-32H,1-2H2,(H,34,35)(H,36,37)(H2,21,23,24)(H3,22,27,28,33)/t6-,7-,10-,11-,12-,13-,18-,19-/m1/s1 |
| InChIKey | XRILCFTWUCUKJR-INFSMZHSSA-N |
| SMILES | C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C3NC(=NC4=O)N)OP(=O)(OC[C@@H]5[C@H]([C@H]([C@@H](O5)N6C=NC7=C6N=CN=C7N)O)OP(=O)(O1)O)O)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- cGAS-STING ligand-response assay development
Product-specific evaluation notes
Potential advantages
- Defined linkage isomers and counterion forms allow controlled comparisons across cyclic-dinucleotide assay conditions.
Method limitations
- Activity can depend on linkage stereochemistry, receptor variant, cell entry, salt form and assay format; molar calculations should use the exact supplied form.
These points describe 2',3'-cGAMP or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
2',3'-cGAMP disodium salt
Cyclic Dinucleotides · CAS: 2734858-36-5
BX-CDN-00032'3'-c-di-AM(PS)2 (Rp,Rp) disodium salt
Cyclic Dinucleotides · CAS: 1638750-95-4
BX-CDN-00043',3'-cGAMP
Cyclic Dinucleotides · CAS: 849214-04-6
BX-CDN-00052'3'-c-di-AM(PS)2 (Rp,Rp) diammonium salt
Cyclic Dinucleotides · CAS: 1638750-96-5
BX-CDN-00062'3'-c-di-AM(PS)2 (Rp,Rp)
Cyclic Dinucleotides · CAS: 1638241-89-0
BX-CDN-0007c-di-AMP disodium salt
Cyclic Dinucleotides · CAS: 2734909-87-4
Frequently asked questions
Can the package size for 2',3'-cGAMP be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-CDN-0001 and CAS 1441190-66-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not a BX Lab lot specification or product-performance claim.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.