Modified Nucleosides
2',3'-Didehydro-2',3'-dideoxyuridine
Quick view. A uridine analogue with a 2'-3' double bond and no 2'- or 3'-hydroxyl group, commonly abbreviated D4U. CAS 5974-93-6. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2',3'-Didehydro-2',3'-dideoxyuridine is classified as 2',3'-didehydro-2',3'-dideoxy pyrimidine nucleoside (Formula C9H10N2O4; molecular weight 210.19 g/mol).
2',3'-Didehydro-2',3'-dideoxyuridine — Reported as a starting scaffold for preparation of 3'-carbon-substituted pyrimidine nucleoside analogues.
For 2',3'-Didehydro-2',3'-dideoxyuridine, polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
Names and search terms
Confirmed or normalized name variants
- 2',3'-Dideoxy-2',3'-didehydrouridine
- D4U
Useful catalog search terms
- 5974-93-6
- NZXWQUCGACTHLK-POYBYMJQSA-N
Physicochemical data
| InChIKey | NZXWQUCGACTHLK-POYBYMJQSA-N |
|---|---|
| InChI | InChI=1S/C9H10N2O4/c12-5-6-1-2-8(15-6)11-4-3-7(13)10-9(11)14/h1-4,6,8,12H,5H2,(H,10,13,14)/t6-,8+/m0/s1 |
| SMILES | C1=C[C@@H](O[C@@H]1CO)N2C=CC(=O)NC2=O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 2',3'-Didehydro-2',3'-dideoxyuridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2',3'-Didehydro-2',3'-dideoxyuridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0605 and CAS 5974-93-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not a BX Lab lot specification or product-performance claim.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.