Modified Nucleosides
2',3'-Dideoxy-2',3'-didehydro-uridine
Quick view. We supply 2',3'-Dideoxy-2',3'-didehydro-uridine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 5974-93-6. Catalog target purity: Specification on request.
Product profile
2',3'-Dideoxy-2',3'-didehydro-uridine is classified as nucleoside or protected nucleoside intermediate (Formula C9H10N2O4; molecular weight 210.19).
2',3'-Dideoxy-2',3'-didehydro-uridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2',3'-Dideoxy-2',3'-didehydro-uridine, storage: Sealed in dry,Room Temperature.
Names and search terms
Confirmed or normalized name variants
- 2',3'-Didehydro-2',3'-dideoxyuridine
- Uridine,2',3'-didehydro-2',3'-dideoxy-
- 2',3'-DIDEHYDROURIDINE-2',3'-DIDEOXYURIDINE
- 2’,3’-Dideoxy-2’,3’-didehydro-uridine, ddddU
- 1-[5β-(Hydroxymethyl)-2,5-dihydrofuran-2β-yl]uracil
- 1-(2,3-DIDEOXY-BETA-D-GLYCEROPENT-2-ENOFURANOSYL)URACIL
- 1-[(2R,5S)-2,5-Dihydro-5-(hydroxymethyl)furan-2-yl]pyrimidine-2,4(1H,3H)-dione
- 1-((2R,5S)-5-(Hydroxymethyl)-2,5-dihydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
Useful catalog search terms
- CAS 5974-93-6
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C9H10N2O4/c12-5-6-1-2-8(15-6)11-4-3-7(13)10-9(11)14/h1-4,6,8,12H,5H2,(H,10,13,14)/t6-,8+/m0/s |
|---|---|
| InChIKey | NZXWQUCGACTHLK-POYBYMJQSA-N |
| SMILES | C1=C[C@@H](O[C@@H]1CO)N2C=CC(=O)NC2=O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 2',3'-Dideoxy-2',3'-didehydro-uridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2',3'-Dideoxy-2',3'-didehydro-uridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0605 and CAS 5974-93-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.