Modified Nucleosides
2',3'-dideoxy adenosine
Quick view. We supply 2',3'-dideoxy adenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 4097-22-7. Catalog target purity: Specification on request.
Product profile
2',3'-dideoxy adenosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H13N5O2; molecular weight 235.24).
2',3'-dideoxy adenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2',3'-dideoxy adenosine, reported solubility: DMF: 1 mg/mL; DMSO: 2 mg/mL; Ethanol: Slightly soluble. Storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- dideoxyadenosine
- BETA-D-2',3'-DIDEOXYADENOSINE
- DDA
- 2’,3’-dideoxy-adenosin
- 2',3'-Dideoxy-D-adenosine
- 9-(2,3-Dideoxy-beta-D-ribofuranosyl)adenine
- 2',3'-DIDEOXYADENOSINE extapure
- [(2S,5R)-5-(6-Aminopurin-9-yl)oxolan-2-yl]methanol
Useful catalog search terms
- CAS 4097-22-7
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H13N5O2/c11-9-8-10(13-4-12-9)15(5-14-8)7-2-1-6(3-16)17-7/h4-7,16H,1-3H2,(H2,11,12,13)/t6-,7+/m0/s |
|---|---|
| InChIKey | WVXRAFOPTSTNLL-NKWVEPMBSA-N |
| SMILES | C1C[C@@H](O[C@@H]1CO)N2C=NC3=C2N=CN=C3N |
| Melting point | 181-184 °C(lit.) |
| Boiling point | 377.64°C (rough estimate) |
| Density | 1.2455 (rough estimate) |
| pKa | pKa 3.84(H₂O t=25.0±0. I=0.01) (Uncertain) |
| Form | Powder |
| Color | White to Off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 2',3'-dideoxy adenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2',3'-dideoxy adenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0528 and CAS 4097-22-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.