Modified Nucleosides
2',3'-dideoxyinosine
Quick view. We supply 2',3'-dideoxyinosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 69655-05-6. Catalog target purity: Specification on request.
Product profile
2',3'-dideoxyinosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H12N4O3; molecular weight 236.23).
2',3'-dideoxyinosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2',3'-dideoxyinosine, reported solubility: Soluble in DMSO or methanol. Storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- didanosine
- 2',3'-DIDEOXYINDOSINE
- DDI
- DDLNO
- dideoxyinosine
- VIDEX
- 2’,3’-dideoxy-inosin
- 2’,3’-didoxyinosine
Useful catalog search terms
- CAS 69655-05-6
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H12N4O3/c15-3-6-1-2-7(17-6)14-5-13-8-9(14)11-4-12-10(8)16/h4-7,15H,1-3H2,(H,11,12,16)/t6-,7+/m0/s |
|---|---|
| InChIKey | BXZVVICBKDXVGW-NKWVEPMBSA-N |
| SMILES | C1C[C@@H](O[C@@H]1CO)N2C=NC3=C2NC=NC3=O |
| Melting point | 193-195 °C |
| Boiling point | 193-195 C |
| Density | 1.2917 (rough estimate) |
| pKa | 9.12(at 25℃) |
| Form | Powder |
| Color | White to Off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 2',3'-dideoxyinosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2',3'-dideoxyinosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0640 and CAS 69655-05-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.