Modified Nucleosides
2',3'-Dideoxyuridine
Quick view. We supply 2',3'-Dideoxyuridine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 5983-09-5. Catalog target purity: Specification on request.
Product profile
2',3'-Dideoxyuridine is classified as nucleoside or protected nucleoside intermediate (Formula C9H12N2O4; molecular weight 212.2).
2',3'-Dideoxyuridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2',3'-Dideoxyuridine, reported solubility: DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: Slightly soluble; PBS (pH 7.2): 5 mg/ml. Storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- 1-(2',3'-DIDEOXY-BETA-RIBOFURANOSYL)URACIL
- BETA-D-2',3'-DIDEOXYURIDINE
- DDU
- 2',3'-Dideoxy-D-uridine
- 2'', 3''-DIDEOXYURIDINE (DDU)
Useful catalog search terms
- CAS 5983-09-5
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C9H12N2O4/c12-5-6-1-2-8(15-6)11-4-3-7(13)10-9(11)14/h3-4,6,8,12H,1-2,5H2,(H,10,13,14)/t6-,8+/m0/s |
|---|---|
| InChIKey | BTOTXLJHDSNXMW-POYBYMJQSA-N |
| SMILES | OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)CC1 |
| Melting point | 127-129 °C(lit.) |
| Density | 1.397±0.06 g/cm3(Predicted) |
| pKa | 9.39±0.10(Predicted) |
| Form | A solid |
| Color | White to off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 2',3'-Dideoxyuridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2',3'-Dideoxyuridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0607 and CAS 5983-09-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.