Amino-modified Nucleosides
2-Amino-2',3'-bis-O-(2-methoxyethyl)adenosine
Quick view. A 2-aminoadenosine derivative bearing 2-methoxyethyl groups at the 2'- and 3'-oxygen positions, identified by CAS 847647-19-2. CAS 847647-19-2. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2-Amino-2',3'-bis-O-(2-methoxyethyl)adenosine is classified as amino-modified nucleosides (Formula C16H26N6O6; molecular weight 398.41).
2-Amino-2',3'-bis-O-(2-methoxyethyl)adenosine provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 2-Amino-2',3'-bis-O-(2-methoxyethyl)adenosine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- 2-Amino-2',3'-bis-O-MOE-adenosine
Useful catalog search terms
- CAS 847647-19-2
- PubChem CID 168449013
Physicochemical data
| PubChem CID | 168449013 |
|---|---|
| InChIKey | IDFCDQNVQDKUMQ-SDBHATRESA-N |
| Nucleoside scaffold | 2-aminoadenosine |
| Base amino pattern | 2,6-diaminopurine |
| Sugar substitution | 2',3'-bis-O-(2-methoxyethyl) |
| Free hydroxyl | 5'-OH |
| InChI | InChI=1S/C16H26N6O6/c1-24-3-5-26-11-9(7-23)28-15(12(11)27-6-4-25-2)22-8-19-10-13(17)20-16(18)21-14(10)22/h8-9,11-12,15,23H,3-7H2,1-2H3,(H4,17,18,20,21)/t9-,11-,12-,15-/m1/s1 |
| SMILES | COCCO[C@@H]1[C@H](O[C@H]([C@@H]1OCCOC)N2C=NC3=C(N=C(N=C32)N)N)CO |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe 2-Amino-2',3'-bis-O-(2-methoxyethyl)adenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2-Amino-2',3'-bis-O-(2-methoxyethyl)adenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0238 and CAS 847647-19-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.