Amino-modified Nucleosides
2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-methyluridine
Quick view. A 5'-O-DMT-protected 2'-amino-2'-deoxy-5-methyluridine building block for structure-specific protected nucleoside and nucleotide synthesis research. CAS 158665-47-5. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-methyluridine is classified as amino-modified nucleosides (Formula C31H33N3O7; molecular weight 559.60).
2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-methyluridine — 5'-O-DMT-protected 2'-amino-2'-deoxy-5-methyluridine building block for structure-specific protected nucleoside and nucleotide synthesis research.
For 2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-methyluridine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- 2'-Amino-2'-deoxy-5'-O-DMT-5-methyluridine
Useful catalog search terms
- CAS 158665-47-5
- PubChem CID 102211289
Physicochemical data
| PubChem CID | 102211289 |
|---|---|
| InChIKey | TUSABYUHVBHWDJ-LTGLEFCMSA-N |
| IUPAC name | 1-[(2R,3R,4S,5R)-3-amino-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]-5-methylpyrimidine-2,4-dione |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)N |
| Sugar modification | 2'-amino-2'-deoxy |
| Nucleobase modification | 5-methyl |
| Protecting group | 5'-O-(4,4'-dimethoxytrityl) |
| InChI | InChI=1S/C31H33N3O7/c1-19-17-34(30(37)33-28(19)36)29-26(32)27(35)25(41-29)18-40-31(20-7-5-4-6-8-20,21-9-13-23(38-2)14-10-21)22-11-15-24(39-3)16-12-22/h4-17,25-27,29,35H,18,32H2,1-3H3,(H,33,36,37)/t25-,26-,27-,29-/m1/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-methyluridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-methyluridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0030 and CAS 158665-47-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.