Amino-modified Nucleosides
2-Amino-2'-O-(2-propyn-1-yl)adenosine
Quick view. A 2-aminoadenosine derivative bearing a 2'-O-propargyl substituent, CAS 1451256-04-4. CAS 1451256-04-4. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2-Amino-2'-O-(2-propyn-1-yl)adenosine is classified as amino-modified nucleosides (Formula C13H16N6O4; molecular weight 320.30 g/mol).
2-Amino-2'-O-(2-propyn-1-yl)adenosine — A 2-amino, 2'-O-propargyl adenosine derivative for research use in modified purine nucleoside synthesis.
For 2-Amino-2'-O-(2-propyn-1-yl)adenosine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- 2'-O-Propargyl-2-aminoadenosine
- GL101083
Useful catalog search terms
- 1451256-04-4
- AGYDCNMIAHDTSH-WOUKDFQISA-N
- PubChem CID 102339225
Physicochemical data
| Nucleobase | 2,6-Diaminopurine |
|---|---|
| 2' substituent | 2'-O-Propargyl ether |
| Hydroxyl state | Free 3' and 5' hydroxyls |
| PubChem CID | 102339225 |
| InChIKey | AGYDCNMIAHDTSH-WOUKDFQISA-N |
| InChI | InChI=1S/C13H16N6O4/c1-2-3-22-9-8(21)6(4-20)23-12(9)19-5-16-7-10(14)17-13(15)18-11(7)19/h1,5-6,8-9,12,20-21H,3-4H2,(H4,14,15,17,18)/t6-,8-,9-,12-/m1/s1 |
| SMILES | C#CCO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=C(N=C32)N)N)CO)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 2-Amino-2'-O-(2-propyn-1-yl)adenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2-Amino-2'-O-(2-propyn-1-yl)adenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0026 and CAS 1451256-04-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.