Amino-modified Nucleosides
2-Amino-3'-deoxy-3'-fluoroadenosine
Quick view. An unprotected 2-amino purine nucleoside bearing a 3'-fluoro-3'-deoxy sugar modification, CAS 125391-75-5. CAS 125391-75-5. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2-Amino-3'-deoxy-3'-fluoroadenosine is classified as amino-modified nucleosides (Formula C10H13FN6O3; molecular weight 284.25).
2-Amino-3'-deoxy-3'-fluoroadenosine provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 2-Amino-3'-deoxy-3'-fluoroadenosine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- Adenosine, 2-amino-3'-deoxy-3'-fluoro-
- 2-Amino-3'-fluoro-3'-deoxyadenosine
Useful catalog search terms
- CAS 125391-75-5
Physicochemical data
| InChI | InChI=1S/C10H13FN6O3/c11-4-3(1-18)20-9(6(4)19)17-2-14-5-7(12)15-10(13)16-8(5)17/h2-4,6,9,18-19H,1H2,(H4,12,13,15,16)/t3-,4-,6-,9-/m1/s1 |
|---|---|
| InChIKey | BBWXIJICDDYYJZ-DXTOWSMRSA-N |
| Isomeric SMILES | C1=NC2=C(N=C(N=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)F)O)N)N |
| Base modification | 2-amino purine |
| Sugar modification | 3'-fluoro-3'-deoxy |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2-Amino-3'-deoxy-3'-fluoroadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2-Amino-3'-deoxy-3'-fluoroadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0140 and CAS 125391-75-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.