Modified Nucleosides
2'-C-Methyladenosine
Quick view. We supply 2'-C-Methyladenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 15397-12-3. Catalog target purity: ≥95%.
Product profile
2'-C-Methyladenosine is classified as nucleoside or protected nucleoside intermediate (Formula C11H15N5O4; molecular weight 281.27).
2'-C-Methyladenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-C-Methyladenosine, reported solubility: DMF: 5 mg/mL; DMSO: 20 mg/mL; PBS (pH 7.2): 10 mg/mL. Storage: Store at -20°C.
Names and search terms
Confirmed or normalized name variants
- -C-Methyladenosine
- 2'-CMethyl-D-adenosine
- Adenosine, 2'-C-methyl-
- 2'-C-Methyladenosine USP/EP/BP
- 6-Amino-9-(2'-C-methyl-b-D-ribofuranosyl)purine
- 2-(6-AMINOPURIN-9-YL)-5-(HYDROXYMETHYL)-3-METHYLOXOLANE-3,4-DIOL
Useful catalog search terms
- CAS 15397-12-3
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| SMILES | C[C@]1([C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)N)CO)O)O |
|---|---|
| InChIKey | PASOFFRBGIVJET-YRKGHMEHSA-N |
| InChI | InChI=1S/C11H15N5O4/c1-11(19)7(18)5(2-17)20-10(11)16-4-15-6-8(12)13-3-14-9(6)16/h3-5,7,10,17-19H,2H2,1H3,(H2,12,13,14)/t5-,7-,10-,11-/m1/s |
| Boiling point | 643.4±65.0 °C(Predicted) |
| Density | 1.89 |
| pKa | 13.18±0.70(Predicted) |
| Form | A crystalline solid |
| Color | White to off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 2'-C-Methyladenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0319 and CAS 15397-12-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.