Halogenated Nucleosides
2'-Chloro-2'-deoxyuridine
Quick view. We supply 2'-Chloro-2'-deoxyuridine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 4753-04-2. Catalog target purity: Specification on request.
Product profile
2'-Chloro-2'-deoxyuridine is classified as nucleoside or protected nucleoside intermediate (Formula C9H11ClN2O5; molecular weight 262.65).
2'-Chloro-2'-deoxyuridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-Chloro-2'-deoxyuridine, storage: -20°C.
Names and search terms
Confirmed or normalized name variants
- 1-(2-Chloro-2-deoxypentofuranosyl)-4-hydroxypyrimidin-2(1H)-one
- NSC 526746
- Uridine, 2'-chloro-2'-deoxy-
Useful catalog search terms
- CAS 4753-04-2
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| InChI | InChI=1S/C9H11ClN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h1-2,4,6-8,13,15H,3H2,(H,11,14,16) |
|---|---|
| InChIKey | XOTUXDQKWDTKSI-UHFFFAOYSA-N |
| SMILES | O=c1nc(O)ccn1C1OC(CO)C(O)C1Cl |
| Melting point | 207-212 °C (decomp) |
| Density | 1.67±0.1 g/cm3(Predicted) |
| pKa | 9.39±0.10(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 2'-Chloro-2'-deoxyuridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0115 and CAS 4753-04-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.