Modified Nucleotides
2'-F-m7GMP Ammonium Salt
Quick view. An ammonium salt of N7-methyl guanosine 5'-monophosphate bearing a 2'-fluoro substituent and an unprotected 3'-hydroxyl group. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2'-F-m7GMP Ammonium Salt is classified as modified nucleotides.
2'-F-m7GMP Ammonium Salt is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For 2'-F-m7GMP Ammonium Salt, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 5'-Guanylic acid, 7-methyl-2'-deoxy-2'-fluoro-, inner salt, ammonium salt
Useful catalog search terms
- 2'-fluoro m7GMP ammonium salt
Physicochemical data
| Salt form | Ammonium salt |
|---|---|
| Counterion stoichiometry | Not specified |
| Base modification | N7-methyl guanine |
| Sugar modification | 2'-fluoro |
| Hydroxyl state | 3' hydroxyl unprotected |
| Phosphate state | 5'-monophosphate |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
- Cap analog selection can influence capping efficiency, orientation and downstream translation-related performance.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
- Capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
These points describe 2'-F-m7GMP Ammonium Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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BX-INTE-0021Im-3'-OMe-GMP
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Frequently asked questions
Can the package size for 2'-F-m7GMP Ammonium Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0026, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Modified Nucleotides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.