Modified Nucleotides
3'-OMe-GMP
Quick view. 3'-O-Methylguanosine-5'-monophosphate, a guanosine nucleotide with a 3'-O-methyl group and a 5'-monophosphate; identity is supported by CAS 400806-41-9 and BroadPharm BP-58805. CAS 400806-41-9. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
3'-OMe-GMP is classified as modified nucleotides (Formula C11H16N5O8P; molecular weight 377.30).
3'-OMe-GMP can be evaluated in terminally blocked nucleotide, cap-chemistry and analytical-reference workflows where 3′-O-methylation changes extension or end-group reactivity.
For 3'-OMe-GMP, the 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
Names and search terms
Confirmed or normalized name variants
- 3'-O-Methylguanosine-5'-Monophosphate
- BP-58805
Useful catalog search terms
- CAS 400806-41-9
Physicochemical data
| Identity | 3'-O-Methylguanosine-5'-Monophosphate |
|---|---|
| Modification pattern | 3'-O-methyl |
| Phosphate state | 5'-monophosphate |
| Supplier catalog code | BP-58805 |
| InChI | InChI=1S/C11H16N5O8P/c1-22-7-4(2-23-25(19,20)21)24-10(6(7)17)16-3-13-5-8(16)14-11(12)15-9(5)18/h3-4,6-7,10,17H,2H2,1H3,(H2,19,20,21)(H3,12,14,15,18)/t4-,6-,7-,10-/m1/s1 |
| InChIKey | JGYKGFFURACNNS-KQYNXXCUSA-N |
| SMILES | CO[C@H]1[C@@H](O)[C@H](n2cnc3c(O)nc(=N)[nH]c32)O[C@@H]1COP(=O)(O)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 3′-O-methylation provides a defined blocked ribose terminus and is analytically distinguishable from the corresponding 2′-O-methyl isomer.
Method limitations
- The 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
These points describe 3'-OMe-GMP or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 3'-OMe-GMP be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-INTE-0014 and CAS 400806-41-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
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