Halogenated Nucleosides
2-Fluoro-6-O-[2-(4-nitrophenyl)ethyl]-2'-deoxyinosine
Quick view. A 2'-deoxyinosine derivative bearing fluorine at purine C2 and a 2-(4-nitrophenyl)ethyl group at O6, CAS 132183-39-2. CAS 132183-39-2. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
![Chemical structure of 2-Fluoro-6-O-[2-(4-nitrophenyl)ethyl]-2'-deoxyinosine](/structures/50b5e531c30393f9.svg)
Product profile
2-Fluoro-6-O-[2-(4-nitrophenyl)ethyl]-2'-deoxyinosine is classified as halogenated nucleosides (Formula C18H18FN5O6; molecular weight 419.37).
2-Fluoro-6-O-[2-(4-nitrophenyl)ethyl]-2'-deoxyinosine — A 2024 Nucleic Acids Research study used this compound as the starting nucleoside in a preparation of N2-heptynyl-dG.
For 2-Fluoro-6-O-[2-(4-nitrophenyl)ethyl]-2'-deoxyinosine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 2-Fluoro-O6-(2-(p-nitrophenyl)ethyl)-2'-deoxyinosine
- 2'-Deoxy-2-fluoro-6-O-[2-(4-nitrophenyl)ethyl]inosine
Useful catalog search terms
- CAS 132183-39-2
- Berry PR 3842
- CDQYNHZEMPHEMV-BFHYXJOUSA-N
- PubChem CID 11091061
Physicochemical data
| Berry product number | PR 3842 |
|---|---|
| Purine substitution | 2-fluoro |
| O-protecting group | 6-O-[2-(4-nitrophenyl)ethyl] (NPE) |
| Sugar modification | 2'-deoxy |
| PubChem CID | 11091061 |
| InChIKey | CDQYNHZEMPHEMV-BFHYXJOUSA-N |
| InChI | InChI=1S/C18H18FN5O6/c19-18-21-16-15(20-9-23(16)14-7-12(26)13(8-25)30-14)17(22-18)29-6-5-10-1-3-11(4-2-10)24(27)28/h1-4,9,12-14,25-26H,5-8H2/t12-,13+,14+/m0/s1 |
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(N=C3OCCC4=CC=C(C=C4)[N+](=O)[O-])F)CO)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2-Fluoro-6-O-[2-(4-nitrophenyl)ethyl]-2'-deoxyinosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2-Fluoro-6-O-[2-(4-nitrophenyl)ethyl]-2'-deoxyinosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0171 and CAS 132183-39-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not a BX Lab lot specification or product-performance claim.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.