Modified Nucleosides
2-Methylthio-N6-iso-pentenyl adenosine
Quick view. We supply 2-Methylthio-N6-iso-pentenyl adenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 20859-00-1. Catalog target purity: Specification on request.
Product profile
2-Methylthio-N6-iso-pentenyl adenosine is classified as nucleoside or protected nucleoside intermediate (Formula C16H23N5O4S; molecular weight 381.45).
2-Methylthio-N6-iso-pentenyl adenosine — 2-Methylthio-N6-isopentenyladenosine is located at position 37 in tRNAs that read codons starting with uridine. 2-Methylthio-N6-isopentenyladenosine in trpT(Su9) suppressor tRNA increase the efficiency of the tRNA by protecting it from ribosomal proofreading which is induced by codon context.
For 2-Methylthio-N6-iso-pentenyl adenosine, reported solubility: soluble in No data available.
Names and search terms
Confirmed or normalized name variants
- 2-methylthio-N(6)-(Delta(2)-isopentenyl)adenosine
- 2MSA
- ms2i6A
- ms2i6 2 6
- Adenosine Related Compound 9
- Methylthioisopentenyladenosine
- 2-(Methylthio)-N-isopentenyladenosine
- 2-Methylthio-N6-isopentenyladenosine NEW
Useful catalog search terms
- CAS 20859-00-1
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C16H23N5O4S/c1-8(2)4-5-17-13-10-14(20-16(19-13)26-3)21(7-18-10)15-12(24)11(23)9(6-22)25-15/h4,7,9,11-12,15,22-24H,5-6H2,1-3H3,(H,17,19,20)/t9-,11-,12-,15-/m1/s |
|---|---|
| InChIKey | VZQXUWKZDSEQRR-SDBHATRESA-N |
| SMILES | CC(=CCNC1=NC(=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)SC)C |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 2-Methylthio-N6-iso-pentenyl adenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 2-Methylthio-N6-iso-pentenyl adenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0347 and CAS 20859-00-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.
