Modified Nucleotides
2'-O-4'-C-Locked-m7GMP Ammonium Salt
Quick view. We supply 2'-O-4'-C-Locked-m7GMP Ammonium Salt as an LNA-style locked N7-methyl GMP cap-analog reagent for mRNA cap and modified nucleotide research. A public CAS number is not assigned for this exact form. Catalog target purity: Specification on request.
Product profile
2'-O-4'-C-Locked-m7GMP Ammonium Salt is classified as rna cap analog or cap-related nucleotide.
2'-O-4'-C-Locked-m7GMP Ammonium Salt can support enzyme-substrate, in-vitro transcription, polymerase-screening or analytical-reference studies as appropriate to its phosphate state.
For 2'-O-4'-C-Locked-m7GMP Ammonium Salt, capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
Names and search terms
Useful catalog search terms
- RNA cap analog or cap-related nucleotide
- conformationally locked sugar
- Modified Nucleotides
Physicochemical data
| Key chemistry motifs | conformationally locked sugar |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, salt/counterion, assay basis, water content and enzyme compatibility.
- Related uses include LC-MS/HPLC method development and comparison with native or modified nucleotide controls.
Product-specific evaluation notes
Potential advantages
- Cap analog selection can influence capping efficiency, orientation and downstream translation-related performance.
Method limitations
- Capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
These points describe 2'-O-4'-C-Locked-m7GMP Ammonium Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-O-4'-C-Locked-m7GMP Ammonium Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0030, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleotides product family and its named chemistry.