2'-O-Me Nucleosides
2'-O-Methylinosine
Quick view. A 2'-O-methylinosine nucleoside building block for nucleoside and oligonucleotide synthesis research. CAS 3881-21-8. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2'-O-Methylinosine is classified as 2'-o-me nucleosides (Formula C11H14N4O5; molecular weight 282.25).
2'-O-Methylinosine — Modified inosine nucleoside building block for nucleoside and oligonucleotide synthesis research.
For 2'-O-Methylinosine, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- 2'-O-Me-rI
- 2'-O-methyl-D-inosine
Useful catalog search terms
- CAS 3881-21-8
Physicochemical data
| InChIKey | HPHXOIULGYVAKW-IOSLPCCCSA-N |
|---|---|
| Nucleobase | Hypoxanthine |
| Sugar modification | 2'-O-methyl |
| InChI | InChI=1S/C11H14N4O5/c1-19-8-7(17)5(2-16)20-11(8)15-4-14-6-9(15)12-3-13-10(6)18/h3-5,7-8,11,16-17H,2H2,1H3,(H,12,13,18)/t5-,7-,8-,11-/m1/s1 |
| SMILES | CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C2NC=NC3=O)CO)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 2'-O-Methylinosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-O-Methylinosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2OMN-0005 and CAS 3881-21-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-O-Me Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.