Modified Nucleotides
2'-O-Methyl-5-methyluridine 5'-triphosphate triethylammonium salt
Quick view. The triethylammonium salt designation of 2'-O-methyl-5-methyluridine 5'-triphosphate; reviewed formula and molecular weight values refer to the acid form. CAS 444789-41-7. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2'-O-Methyl-5-methyluridine 5'-triphosphate triethylammonium salt is classified as 2'-o-methyl-5-methyl uridine 5'-triphosphate salt.
2'-O-Methyl-5-methyluridine 5'-triphosphate triethylammonium salt supports modified RNA/antisense designs where methylated ribose positions are used to improve stability or reduce unwanted immune stimulation.
For 2'-O-Methyl-5-methyluridine 5'-triphosphate triethylammonium salt, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- 2'-O-Methyl-5-methyluridine 5'-triphosphate
Useful catalog search terms
- 444789-41-7
- CZTUINPWSQLSKN-FDDDBJFASA-N
Physicochemical data
| CAS basis | Catalog CAS resolves to the acid-form PubChem component; triethylammonium stoichiometry is not specified |
|---|---|
| Salt form | Triethylammonium salt |
| Counterion stoichiometry | Not specified |
| Structure representation | Acid-form component; triethylammonium counterions are not represented |
| PubChem CID (acid form) | 87255687 |
| Molecular formula (acid form) | C11H19N2O15P3 |
| Molecular weight (acid form) | 512.19 g/mol |
| IUPAC name (acid form) | [hydroxy-[[(2R,3R,4R,5R)-3-hydroxy-4-methoxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl] phosphono hydrogen phosphate |
| InChIKey (acid form) | CZTUINPWSQLSKN-FDDDBJFASA-N |
| InChI (acid form) | InChI=1S/C11H19N2O15P3/c1-5-3-13(11(16)12-9(5)15)10-8(24-2)7(14)6(26-10)4-25-30(20,21)28-31(22,23)27-29(17,18)19/h3,6-8,10,14H,4H2,1-2H3,(H,20,21)(H,22,23)(H,12,15,16)(H2,17,18,19)/t6-,7-,8-,10-/m1/s1 |
| SMILES (acid form) | CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)OC |
| Canonical SMILES (acid form) | CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)OC |
| Connectivity SMILES (acid form) | CC1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)OC |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 2'-O-Methyl-5-methyluridine 5'-triphosphate triethylammonium salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-O-Methyl-5-methyluridine 5'-triphosphate triethylammonium salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MODN-0173 and CAS 444789-41-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact BX Lab product, supplied form, lot specification, availability or performance.
Technology platforms
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