Modified Nucleotides
2'-O-Methyl-5-methyluridine 5'-triphosphatetriethylammonium salt
Quick view. We supply 2'-O-Methyl-5-methyluridine 5'-triphosphatetriethylammonium salt as a 2'-O-methyl nucleotide used to prepare or evaluate modified RNA with improved nuclease resistance and altered immune recognition. CAS 444789-41-7. Catalog target purity: Specification on request.
Structure and identity
The structure drawing for this item is being finalized. Use the CAS number and machine-readable identifiers below to confirm the requested protecting groups, stereochemistry, salt or counterion and hydration state before ordering.
CAS, molecular formula, SMILES or InChI data are shown below when available.
We withhold a drawing when a related compound, alternate salt or incompletely specified stereoisomer could be mistaken for the requested material.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
2'-O-Methyl-5-methyluridine 5'-triphosphatetriethylammonium salt is classified as nucleotide or nucleotide analog (Formula C11H19N2O15P3; molecular weight 512.19).
2'-O-Methyl-5-methyluridine 5'-triphosphatetriethylammonium salt can support enzyme-substrate, in-vitro transcription, polymerase-screening or analytical-reference studies as appropriate to its phosphate state.
For 2'-O-Methyl-5-methyluridine 5'-triphosphatetriethylammonium salt, modification benefits are context-dependent; transcript length, substitution level, enzyme system and analytical purity can change the observed outcome.
Names and search terms
Confirmed or normalized name variants
- 2'-O-Methyl-5-methyluridine 5'-triphosphate
- 2’-O-Methyl-5-methyluridine 5’-triphosphate triethylammonium salt [acid form
Useful catalog search terms
- CAS 444789-41-7
- Nucleotide or nucleotide analog
- 2'-O-methyl modification
- triphosphate group
- Modified Nucleotides
Physicochemical data
| Key chemistry motifs | 2'-O-methyl modification; triphosphate group |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, salt/counterion, assay basis, water content and enzyme compatibility.
- Related uses include LC-MS/HPLC method development and comparison with native or modified nucleotide controls.
Product-specific evaluation notes
Potential advantages
- Base modifications can tune RNA stability, translation behavior, duplex properties or analytical discrimination versus native bases.
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Modification benefits are context-dependent; transcript length, substitution level, enzyme system and analytical purity can change the observed outcome.
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 2'-O-Methyl-5-methyluridine 5'-triphosphatetriethylammonium salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
3'-OMe-GDP Disodium Salt
Modified Nucleotides · CAS: 78771-34-3
BX-INTE-00143'-OMe-GMP
Modified Nucleotides · CAS: 400806-41-9
BX-INTE-00153'-OMe-GMP TEA Salt
Modified Nucleotides · CAS: 860605-85-2
BX-INTE-0021Im-3'-OMe-GMP
Modified Nucleotides · CAS: 1005791-93-4
BX-INTE-0023Im-GDP
Modified Nucleotides · CAS: 1199264-75-9
BX-MN-0025(-)-Emtricitabine Triphosphate Tetrasodium Salt
Modified Nucleotides · CAS: 1188407-46-6
Frequently asked questions
Can the package size for 2'-O-Methyl-5-methyluridine 5'-triphosphatetriethylammonium salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MODN-0173 and CAS 444789-41-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 2'-O-Methyl-5-methyluridine 5'-triphosphatetriethylammonium salt or the named structural feature represented by this product.