Reverse Phosphoramidites
N6-Benzoyl-2'-O-TBDMS-3'-O-DMTr-adenosine-5'-CE phosphoramidite
Quick view. A reverse-orientation N6-benzoyl adenosine phosphoramidite bearing 2'-O-TBDMS and 3'-O-DMTr protection with a 5'-cyanoethyl N,N-diisopropylphosphoramidite group. CAS 1146146-22-6. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.

Product profile
N6-Benzoyl-2'-O-TBDMS-3'-O-DMTr-adenosine-5'-CE phosphoramidite is classified as reverse phosphoramidites (Formula C53H66N7O8PSi; molecular weight 988.21).
N6-Benzoyl-2'-O-TBDMS-3'-O-DMTr-adenosine-5'-CE phosphoramidite — Identity-defined 2'-O-TBDMS rA(Bz) reverse amidite for research workflows involving reverse-orientation solid-phase oligonucleotide synthesis.
For N6-Benzoyl-2'-O-TBDMS-3'-O-DMTr-adenosine-5'-CE phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2'-O-TBDMS-rA(Bz)-CE reverse phosphoramidite
- 3'-DMTr-2'-O-TBDMS-A(Bz)-5'-CE phosphoramidite
- N6-benzoyl-2'-O-TBDMS-3'-O-DMTr-rA-5'-CE phosphoramidite
Useful catalog search terms
- CAS 1146146-22-6
Physicochemical data
| Nucleoside | Adenosine |
|---|---|
| Base protection | N6-Benzoyl |
| 2'-Protecting group | TBDMS |
| 3'-Protecting group | DMTr |
| 5'-Coupling group | 2-Cyanoethyl N,N-diisopropylphosphoramidite |
| Synthesis orientation | Reverse 5'-to-3' |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Frequently asked questions
Can the package size for N6-Benzoyl-2'-O-TBDMS-3'-O-DMTr-adenosine-5'-CE phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-RP-0014 and CAS 1146146-22-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Reverse Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
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