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BX LAB PRODUCT CATEGORY

Reverse Phosphoramidites

Quick view. Reverse-orientation phosphoramidites for 5′→3′ synthesis strategies, end modification and specialized sequence design. This category currently includes 15 products. Reverse Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.

Products15
Use scopeResearch use only
Pack sizeCustomized to requirements
SupportSelection and custom synthesis review

Category guide

Typical use

Reverse Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.

How to select

Confirm base and sugar identity, protecting groups, stereochemistry, linker or label position, and compatibility with coupling and deprotection conditions.

How to qualify

Review identity, chromatographic purity, phosphorus-related quality attributes, water sensitivity and performance in a short test sequence.

Product-family considerations

Common advantages
  • Phosphoramidite chemistry is modular, automated and compatible with fast sequence iteration.
  • Modified sugar, base or linker motifs let researchers tune duplex stability, specificity, hydrophobicity, steric profile and downstream conjugation options.
Common limitations
  • Modified amidites can require adjusted coupling time, activator choice, deprotection conditions and analytical release methods.
  • Moisture sensitivity and storage history are important because degraded amidite can reduce coupling efficiency.

Category literature

These publications provide background for the Reverse Phosphoramidites product family. Individual product pages only show additional product- or feature-relevant references.

Selection checklist

Exact identityMatch the canonical name with a CAS number, structure, SMILES or drawing; confirm stereochemistry, protecting groups and salt form where applicable.
SpecificationDefine target purity, analytical method, water or residual-solvent concerns and any application-specific acceptance limits.
Workflow fitShare the reaction, enzyme, sequence, solvent system, support or analytical method used to evaluate compatibility.
Supply needProvide initial quantity, expected future scale, packaging preference, timeline and documentation requirements.

15 products

Chemical structure of 3'-O-DMTr-2'-O-Me-A(Bz)-5'-CE-Phosphoramidite3'-O-DMTr-2'-O-Me-A(Bz)-5'-CE-Phosphoramidite

≥98% · CAS: 1309448-27-8

BX-RP-0013
Chemical structure of 2'-F-dG(iBu)-CE-Reverse Phosphoramidite2'-F-dG(iBu)-CE-Reverse Phosphoramidite

≥98% · CAS: 2757763-07-6

BX-RP-0016
Chemical structure of 3'-O-DMTr-2'-O-(2-methoxyethyl)-5-methyluridine-5'-O-CED phosphoramidite3'-O-DMTr-2'-O-(2-methoxyethyl)-5-methyluridine-5'-O-CED phosphoramidite

≥98% · CAS: 1345715-43-6

BX-RP-0030
Chemical structure of reverse-orientation 2'-fluoro-dA(Bz) phosphoramidite3'-O-DMTr-2'-F-dA(Bz)-5'-CE-Phosphoramidite

≥98% · CAS: 2227293-35-6

BX-RP-0001
Chemical structure of 3'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-5'-CE-Phosphoramidite3'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-5'-CE-Phosphoramidite

≥98% · CAS: N/A

BX-RP-0002
Chemical structure of 3'-O-DMTr-2'-O-MOE-rA(Bz)-5'-CE-Phosphoramidite3'-O-DMTr-2'-O-MOE-rA(Bz)-5'-CE-Phosphoramidite

≥98% · CAS: N/A

BX-RP-0003
Chemical structure of reverse-orientation 2'-O-MOE-rG(iBu) phosphoramidite3'-O-DMTr-2'-O-MOE-rG(iBu)-5'-CE-Phosphoramidite

≥98% · CAS: 725223-44-9

BX-RP-0004
Chemical structure of reverse-orientation 2'-O-methyluridine phosphoramidite3'-O-DMTr-2'-O-Me-rU-5'-CE-Phosphoramidite

≥98% · CAS: 2721427-32-1

BX-RP-0006
Chemical structure of reverse-orientation dG(dmf) phosphoramidite3'-O-DMTr-2'-dG(dmf)-5'-CE-Phosphoramidite

≥98% · CAS: 261728-23-8

BX-RP-0007
Chemical structure of reverse-orientation thymidine phosphoramidite3'-O-DMTr-2'-dT-5'-CE-Phosphoramidite

≥98% · CAS: 134031-86-0

BX-RP-0008
Chemical structure of reverse dSpacer 5'-CE phosphoramiditeReverse Abasic Phosphoramidite

≥98% · CAS: 401813-16-9

BX-RP-0010
Chemical structure of N6-Benzoyl-3'-O-DMTr-2'-deoxyadenosine-5'-CE phosphoramiditeN6-Benzoyl-3'-O-DMTr-2'-deoxyadenosine-5'-CE phosphoramidite

≥98% · CAS: 140712-82-9

BX-RP-0011
Chemical structure of N6-Benzoyl-2'-O-TBDMS-3'-O-DMTr-adenosine-5'-CE phosphoramiditeN6-Benzoyl-2'-O-TBDMS-3'-O-DMTr-adenosine-5'-CE phosphoramidite

≥98% · CAS: 1146146-22-6

BX-RP-0014
Chemical structure of 2'-OMe-G(iBu)-CE-Reverse Phosphoramidite2'-OMe-G(iBu)-CE-Reverse Phosphoramidite

≥98% · CAS: 2721427-31-0

BX-RP-0020
Chemical structure of 2'-O-MOE-5-Me-C(Bz) reverse phosphoramidite2'-O-MOE-5-Me-C(Bz) reverse phosphoramidite

≥98% · CAS: N/A

BX-RP-0023

Frequently asked questions

What are typical uses for Reverse Phosphoramidites?

Reverse Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.

What should be confirmed before ordering Reverse Phosphoramidites?

Confirm base and sugar identity, protecting groups, stereochemistry, linker or label position, and compatibility with coupling and deprotection conditions.

Are custom quantities or related analogs available?

BX Lab reviews custom package sizes, catalog-adjacent analogs and research-use custom synthesis requests against the target structure, purity, scale and timeline.

Need help selecting a product?

Tell our scientists about your target chemistry, workflow, required purity and scale. We can help identify a catalog product, related analog or custom route.

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