Protected Nucleosides
2'-O-TBDMS-uridine
Quick view. A uridine nucleoside protected as a tert-butyldimethylsilyl ether at the ribose 2'-oxygen. CAS 54925-71-2. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2'-O-TBDMS-uridine is classified as 2'-o-silyl-protected uridine (Formula C15H26N2O6Si; molecular weight 358.46 g/mol).
2'-O-TBDMS-uridine is associated with uridine-containing substrates for U-position incorporation in RNA or modified RNA studies.
For 2'-O-TBDMS-uridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2'-TBDMS-rU
Useful catalog search terms
- 54925-71-2
- 11233661
- AYQZFVZTNUOLCQ-OJAKKHQRSA-N
Physicochemical data
| PubChem CID | 11233661 |
|---|---|
| IUPAC name | 1-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
| InChIKey | AYQZFVZTNUOLCQ-OJAKKHQRSA-N |
| InChI | InChI=1S/C15H26N2O6Si/c1-15(2,3)24(4,5)23-12-11(20)9(8-18)22-13(12)17-7-6-10(19)16-14(17)21/h6-7,9,11-13,18,20H,8H2,1-5H3,(H,16,19,21)/t9-,11-,12-,13-/m1/s1 |
| SMILES | CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)CO)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Frequently asked questions
Can the package size for 2'-O-TBDMS-uridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0255 and CAS 54925-71-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
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