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Modified Nucleosides

3',5'-Bis-O-(tert-butyldiphenylsilyl)thymidine

Quick view. 3',5'-Bis-O-(tert-butyldiphenylsilyl)thymidine is a doubly TBDPS-protected thymidine derivative with CAS 118068-35-2. CAS 118068-35-2. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.

Chemical structure of 3',5'-Bis-O-(tert-butyldiphenylsilyl)thymidine
Chemical structure
Catalog numberBX-MN-0215
CAS number118068-35-2
Purity≥98%
Pack sizeCustom packaging by inquiry

Product profile

Material identity

3',5'-Bis-O-(tert-butyldiphenylsilyl)thymidine is classified as silyl-protected thymidine nucleoside (Formula C42H50N2O5Si2; molecular weight 719.05).

Typical application

3',5'-Bis-O-(tert-butyldiphenylsilyl)thymidine is associated with thymidine-containing building blocks or substrates for DNA synthesis and analytical comparison.

Handling focus

For 3',5'-Bis-O-(tert-butyldiphenylsilyl)thymidine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.

Names and search terms

Confirmed or normalized name variants

Useful catalog search terms

Physicochemical data

Structural featuretert-Butyldiphenylsilyl ethers at 3' and 5'
PubChem CID10556813
InChIInChI=1S/C42H50N2O5Si2/c1-31-29-44(40(46)43-39(31)45)38-28-36(49-51(42(5,6)7,34-24-16-10-17-25-34)35-26-18-11-19-27-35)37(48-38)30-47-50(41(2,3)4,32-20-12-8-13-21-32)33-22-14-9-15-23-33/h8-27,29,36-38H,28,30H2,1-7H3,(H,43,45,46)/t36-,37+,38+/m0/s1
InChIKeyOCFYNDLJERQLMN-YXWIYCFASA-N
SMILESCC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO[Si](C3=CC=CC=C3)(C4=CC=CC=C4)C(C)(C)C)O[Si](C5=CC=CC=C5)(C6=CC=CC=C6)C(C)(C)C

Release documentation

Lot-specific CoA

The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.

Analytical package

Additional HPLC, MS or NMR documentation can be agreed during technical review where available.

Related products

Frequently asked questions

Can the package size for 3',5'-Bis-O-(tert-butyldiphenylsilyl)thymidine be customized?

Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.

What information should be included in a quote request?

Quote catalog number BX-MN-0215 and CAS 118068-35-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.

Product-family literature

These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.

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Technology platforms

Catalog-derived platform membership for navigating related chemistry and verifiable product sets.