Modified Nucleosides
3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)guanosine
Quick view. A stereodefined guanosine derivative bearing cyclic 3',5'-O-TIPDS protection and a free 2'-hydroxyl, CAS 69304-44-5. CAS 69304-44-5. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)guanosine is classified as modified nucleosides (Formula C22H39N5O6Si2; molecular weight 525.70 g/mol).
3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)guanosine — Cyclic 3',5'-O-TIPDS-protected guanosine building block for modified nucleoside chemistry.
For 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)guanosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 3',5'-O-TIPPS-guanosine
- 3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine
Useful catalog search terms
- 69304-44-5
- PubChem CID 136662828
- CWVNMKRKFJYCCC-QTQZEZTPSA-N
Physicochemical data
| PubChem CID | 136662828 |
|---|---|
| IUPAC name | 9-[(6aR,8R,9R,9aS)-9-hydroxy-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-2-amino-1H-purin-6-one |
| InChIKey | CWVNMKRKFJYCCC-QTQZEZTPSA-N |
| InChI | InChI=1S/C22H39N5O6Si2/c1-11(2)34(12(3)4)30-9-15-18(32-35(33-34,13(5)6)14(7)8)17(28)21(31-15)27-10-24-16-19(27)25-22(23)26-20(16)29/h10-15,17-18,21,28H,9H2,1-8H3,(H3,23,25,26,29)/t15-,17-,18-,21-/m1/s1 |
| SMILES | CC(C)[Si]1(OC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C3N=C(NC4=O)N)O)O[Si](O1)(C(C)C)C(C)C)C(C)C |
| Stereochemistry | (6aR,8R,9R,9aS) protected ribose system |
| Protecting group | Cyclic 3',5'-O-TIPDS |
| Free hydroxyl | 2'-OH |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Reference compound for chemical identity research involving 3',5'-O-TIPDS-guanosine.
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Frequently asked questions
Can the package size for 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)guanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0474 and CAS 69304-44-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.