Modified Nucleosides
3',5'-O-(Tetraisopropyldisiloxane-1,3-diyl)-cytidine
Quick view. We supply 3',5'-O-(Tetraisopropyldisiloxane-1,3-diyl)-cytidine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 69304-42-3. Catalog target purity: Specification on request.
Product profile
3',5'-O-(Tetraisopropyldisiloxane-1,3-diyl)-cytidine is classified as nucleoside or protected nucleoside intermediate (Formula C21H39N3O6Si; molecular weight 485.72).
3',5'-O-(Tetraisopropyldisiloxane-1,3-diyl)-cytidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 3',5'-O-(Tetraisopropyldisiloxane-1,3-diyl)-cytidine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- (+)-3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)cytidine
- 3',5'-TIPDS-Cr
- 3'-O,5'-O-[Oxybis(diisopropylsilylene)]cytidine
- 3'-O,5'-O-[Oxybis(diisopropylsilanediyl)]cytidine
- (+)-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxan
- (1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)cytidine
- 3'-O,5'-O-(1,1,3,3-Tetraisopropylpropanedisiloxane-1,3-diyl)cytidine
- Cytidine, 3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-
Useful catalog search terms
- CAS 69304-42-3
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C21H39N3O6Si2/c1-12(2)31(13(3)4)27-11-16-19(29-32(30-31,14(5)6)15(7)8)18(25)20(28-16)24-10-9-17(22)23-21(24)26/h9-10,12-16,18-20,25H,11H2,1-8H3,(H2,22,23,26)/t16-,18-,19-,20-/m1/s |
|---|---|
| InChIKey | KPNSXQNKDQMBAW-VBSBHUPXSA-N |
| SMILES | CC(C)[Si]1(OC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=CC(=NC3=O)N)O)O[Si](O1)(C(C)C)C(C)C)C(C)C |
| Melting point | 248-250 °C(lit.) |
| Boiling point | 517.7±60.0 °C(Predicted) |
| Density | 1.24±0.1 g/cm3(Predicted) |
| pKa | 13.18±0.40(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 3',5'-O-(Tetraisopropyldisiloxane-1,3-diyl)-cytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0636 and CAS 69304-42-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.