Amino-modified Nucleosides
3'-Amino-3'-deoxy-5-fluorouridine
Quick view. A uridine nucleoside bearing a 5-fluoro base substitution and a 3'-amino-3'-deoxy sugar modification, identified by CAS 80955-97-1. CAS 80955-97-1. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
3'-Amino-3'-deoxy-5-fluorouridine is classified as amino-modified nucleosides (Formula C9H12FN3O5; molecular weight 261.21).
3'-Amino-3'-deoxy-5-fluorouridine provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 3'-Amino-3'-deoxy-5-fluorouridine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Useful catalog search terms
- CAS 80955-97-1
- PubChem CID 127258193
Physicochemical data
| PubChem CID | 127258193 |
|---|---|
| InChIKey | WRNOGDJKXUHGEA-UAKXSSHOSA-N |
| Nucleoside scaffold | uridine |
| Base modification | 5-fluoro |
| Sugar modification | 3'-amino-3'-deoxy |
| Hydroxyl state | free 2' and 5' hydroxyls |
| InChI | InChI=1S/C9H12FN3O5/c10-3-1-13(9(17)12-7(3)16)8-6(15)5(11)4(2-14)18-8/h1,4-6,8,14-15H,2,11H2,(H,12,16,17)/t4-,5-,6-,8-/m1/s1 |
| SMILES | C1=C(C(=O)NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)N)O)F |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 3'-Amino-3'-deoxy-5-fluorouridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 3'-Amino-3'-deoxy-5-fluorouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0235 and CAS 80955-97-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.