Amino-modified Nucleosides
3'-beta-Amino-2',3'-dideoxy-5'-O-trityl-5-methyluridine
Quick view. 5-Methyluridine derivative with a 2'-deoxy sugar, a 3'-amino group, and triphenylmethyl protection of the 5'-oxygen. CAS 204688-08-4. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
3'-beta-Amino-2',3'-dideoxy-5'-O-trityl-5-methyluridine is classified as amino-modified nucleosides (Formula C29H29N3O4; molecular weight 483.60 g/mol).
3'-beta-Amino-2',3'-dideoxy-5'-O-trityl-5-methyluridine provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 3'-beta-Amino-2',3'-dideoxy-5'-O-trityl-5-methyluridine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- 1-[(2R,4R,5S)-4-amino-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Useful catalog search terms
- 204688-08-4
- PubChem CID 168435847
Physicochemical data
| PubChem CID | 168435847 |
|---|---|
| Sugar modification | 2'-deoxy and 3'-amino |
| 5' protection | O-triphenylmethyl (trityl) |
| Nucleobase | 5-methyluracil |
| InChIKey | STPRWURKISTIRY-TWJOJJKGSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 3'-beta-Amino-2',3'-dideoxy-5'-O-trityl-5-methyluridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 3'-beta-Amino-2',3'-dideoxy-5'-O-trityl-5-methyluridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0045 and CAS 204688-08-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.