Modified Nucleosides
3'-O-Methylinosine
Quick view. A stereodefined inosine nucleoside methylated at the ribose 3'-oxygen, identified by CAS 75479-64-0. CAS 75479-64-0. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
3'-O-Methylinosine is classified as modified nucleosides (Formula C11H14N4O5; molecular weight 282.25).
3'-O-Methylinosine can be evaluated in terminally blocked nucleotide, cap-chemistry and analytical-reference workflows where 3′-O-methylation changes extension or end-group reactivity.
For 3'-O-Methylinosine, the 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
Names and search terms
Confirmed or normalized name variants
- Inosine, 3'-O-methyl-
Useful catalog search terms
- CAS 75479-64-0
- PubChem CID 136662872
Physicochemical data
| Sugar modification | 3'-O-methyl; 2'-OH retained |
|---|---|
| InChIKey | ABXDBVMGRKZFRC-IOSLPCCCSA-N |
| PubChem CID | 136662872 |
| InChI | InChI=1S/C11H14N4O5/c1-19-8-5(2-16)20-11(7(8)17)15-4-14-6-9(15)12-3-13-10(6)18/h3-5,7-8,11,16-17H,2H2,1H3,(H,12,13,18)/t5-,7-,8-,11-/m1/s1 |
| SMILES | CO[C@@H]1[C@H](O[C@H]([C@@H]1O)N2C=NC3=C2N=CNC3=O)CO |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 3′-O-methylation provides a defined blocked ribose terminus and is analytically distinguishable from the corresponding 2′-O-methyl isomer.
Method limitations
- The 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
These points describe 3'-O-Methylinosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
(S)-cEt-rA
Modified Nucleosides · CAS: 1197033-34-3
BX-OP-0069S-Adenosyl-L-methionine (SAM)
Modified Nucleosides · CAS: 485-80-3
BX-MN-01875-(Carboxyhydroxymethyl)uridine
Modified Nucleosides · CAS: 934743-11-0
BX-MN-0719(R)-N6-(2,3-Dihydro-1H-inden-1-yl)adenosine
Modified Nucleosides · CAS: 96392-15-3
BX-MN-01972,2'-Cyclocytidine hydrochloride
Modified Nucleosides · CAS: 10212-25-6
BX-MN-0199N3-Allyluridine
Modified Nucleosides · CAS: 103951-13-9
Frequently asked questions
Can the package size for 3'-O-Methylinosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0669 and CAS 75479-64-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.