Modified Nucleosides
3'-O-(t-Butyldimethylsilyl)-2'-deoxyadenosine
Quick view. We supply 3'-O-(t-Butyldimethylsilyl)-2'-deoxyadenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 51549-31-6. Catalog target purity: Specification on request.
Product profile
3'-O-(t-Butyldimethylsilyl)-2'-deoxyadenosine is classified as nucleoside or protected nucleoside intermediate (Formula C16H27N5O3Si; molecular weight 365.5).
3'-O-(t-Butyldimethylsilyl)-2'-deoxyadenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 3'-O-(t-Butyldimethylsilyl)-2'-deoxyadenosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- Adenosine, 2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-
- 3'-O-(tert-butyldiMethylsilyl)-2'-deoxyadenosine
Useful catalog search terms
- CAS 51549-31-6
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C16H27N5O3Si/c1-16(2,3)25(4,5)24-10-6-12(23-11(10)7-22)21-9-20-13-14(17)18-8-19-15(13)21/h8-12,22H,6-7H2,1-5H3,(H2,17,18,19)/t10-,11+,12+/m0/s |
|---|---|
| InChIKey | RZJNKNBLADNWHG-QJPTWQEYSA-N |
| SMILES | CC(C)(C)[Si](C)(C)O[C@H]1C[C@@H](O[C@@H]1CO)N2C=NC3=C(N=CN=C32)N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 3'-O-(t-Butyldimethylsilyl)-2'-deoxyadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0577 and CAS 51549-31-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.