Protected Nucleosides
3'-O-tert-Butyldiphenylsilylthymidine
Quick view. A thymidine derivative bearing a 3'-O-tert-butyldiphenylsilyl protecting group, identified by CAS 83467-48-5. CAS 83467-48-5. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
3'-O-tert-Butyldiphenylsilylthymidine is classified as protected nucleosides (Formula C26H32N2O5Si; molecular weight 480.60).
3'-O-tert-Butyldiphenylsilylthymidine is associated with thymidine-containing building blocks or substrates for DNA synthesis and analytical comparison.
For 3'-O-tert-Butyldiphenylsilylthymidine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 3'-O-(t-Butyldiphenylsilyl)thymidine
- 3'-O-TBDPS-thymidine
Useful catalog search terms
- CAS 83467-48-5
- PubChem CID 11016319
Physicochemical data
| PubChem CID | 11016319 |
|---|---|
| InChIKey | HEHSUGMKUBTCGE-YTFSRNRJSA-N |
| Nucleoside scaffold | thymidine |
| Sugar protection | 3'-O-TBDPS |
| Sugar modification | 2'-deoxy |
| Hydroxyl state | free 5' hydroxyl |
| InChI | InChI=1S/C26H32N2O5Si/c1-18-16-28(25(31)27-24(18)30)23-15-21(22(17-29)32-23)33-34(26(2,3)4,19-11-7-5-8-12-19)20-13-9-6-10-14-20/h5-14,16,21-23,29H,15,17H2,1-4H3,(H,27,30,31)/t21-,22+,23+/m0/s1 |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)O[Si](C3=CC=CC=C3)(C4=CC=CC=C4)C(C)(C)C |
| Canonical SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)O[Si](C3=CC=CC=C3)(C4=CC=CC=C4)C(C)(C)C |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Frequently asked questions
Can the package size for 3'-O-tert-Butyldiphenylsilylthymidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0691 and CAS 83467-48-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
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