3'-O-TBDMS Phosphoramidites
N6-Benzoyl-5'-O-DMTr-3'-O-TBDMS-adenosine-2'-CE phosphoramidite
Quick view. A protected adenosine building block bearing N6-benzoyl, 5'-O-DMTr, and 3'-O-TBDMS groups with a 2'-cyanoethyl N,N-diisopropylphosphoramidite functionality. CAS 129451-75-8. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
N6-Benzoyl-5'-O-DMTr-3'-O-TBDMS-adenosine-2'-CE phosphoramidite is classified as 3'-o-tbdms phosphoramidites (Formula C53H66N7O8PSi; molecular weight 988.19).
N6-Benzoyl-5'-O-DMTr-3'-O-TBDMS-adenosine-2'-CE phosphoramidite — Identity-defined 3'-O-TBDMS adenosine 2'-phosphoramidite for research workflows involving solid-phase oligonucleotide synthesis.
For N6-Benzoyl-5'-O-DMTr-3'-O-TBDMS-adenosine-2'-CE phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 3'-O-TBDMS-rA(Bz) phosphoramidite
- 3'-TBDMS-Bz-rA phosphoramidite
- DMT-3'-O-TBDMS-A(Bz)-2'-CE phosphoramidite
Useful catalog search terms
- CAS 129451-75-8
Physicochemical data
| Nucleoside | Adenosine |
|---|---|
| Base protection | N6-Benzoyl |
| 5' protection | DMTr |
| 3'-Protecting group | TBDMS |
| 2'-Coupling group | 2-Cyanoethyl N,N-diisopropylphosphoramidite |
| MDL number | MFCD00274109 |
| PubChem CID | 14376009 |
| InChI | InChI=1S/C53H66N7O8PSi/c1-36(2)60(37(3)4)69(65-32-18-31-54)67-47-46(68-70(10,11)52(5,6)7)44(66-51(47)59-35-57-45-48(55-34-56-49(45)59)58-50(61)38-19-14-12-15-20-38)33-64-53(39-21-16-13-17-22-39,40-23-27-42(62-8)28-24-40)41-25-29-43(63-9)30-26-41/h12-17,19-30,34-37,44,46-47,51H,18,32-33H2,1-11H3,(H,55,56,58,61)/t44-,46-,47-,51-,69?/m1/s1 |
| InChIKey | HRYAQLIYKSXPET-RFMFGJHUSA-N |
| SMILES | CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)O[Si](C)(C)C(C)(C)C |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Related products
Frequently asked questions
Can the package size for N6-Benzoyl-5'-O-DMTr-3'-O-TBDMS-adenosine-2'-CE phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-3OTP-0001 and CAS 129451-75-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 3'-O-TBDMS Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.