3'-O-TBDMS Phosphoramidites
N2-Isobutyryl-5'-O-DMTr-3'-O-TBDMS-guanosine-2'-CE phosphoramidite
Quick view. A protected guanosine building block bearing N2-isobutyryl, 5'-O-DMTr, and 3'-O-TBDMS groups with a 2'-cyanoethyl N,N-diisopropylphosphoramidite functionality. CAS 1445905-51-0. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
N2-Isobutyryl-5'-O-DMTr-3'-O-TBDMS-guanosine-2'-CE phosphoramidite is classified as 3'-o-tbdms phosphoramidites (Formula C50H68N7O9PSi; molecular weight 970.18).
N2-Isobutyryl-5'-O-DMTr-3'-O-TBDMS-guanosine-2'-CE phosphoramidite — Identity-defined 3'-O-TBDMS guanosine 2'-phosphoramidite for research workflows involving solid-phase oligonucleotide synthesis.
For N2-Isobutyryl-5'-O-DMTr-3'-O-TBDMS-guanosine-2'-CE phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 3'-O-TBDMS-rG(iBu) phosphoramidite
- 3'-TBDMS-iBu-rG phosphoramidite
- DMT-3'-O-TBDMS-G(iBu)-2'-CE phosphoramidite
Useful catalog search terms
- CAS 1445905-51-0
Physicochemical data
| InChIKey | JCCWPNDXSMAHGZ-FTZVBZPOSA-N |
|---|---|
| PubChem CID | 135742514 |
| Nucleoside | Guanosine |
| Base protection | N2-Isobutyryl |
| 5' protection | DMTr |
| 3'-Protecting group | TBDMS |
| 2'-Coupling group | 2-Cyanoethyl N,N-diisopropylphosphoramidite |
| MDL number | MFCD30475539 |
| InChI | InChI=1S/C50H68N7O9PSi/c1-32(2)45(58)54-48-53-44-41(46(59)55-48)52-31-56(44)47-43(65-67(63-29-17-28-51)57(33(3)4)34(5)6)42(66-68(12,13)49(7,8)9)40(64-47)30-62-50(35-18-15-14-16-19-35,36-20-24-38(60-10)25-21-36)37-22-26-39(61-11)27-23-37/h14-16,18-27,31-34,40,42-43,47H,17,29-30H2,1-13H3,(H2,53,54,55,58,59)/t40-,42-,43-,47-,67?/m1/s1 |
| SMILES | CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O[Si](C)(C)C(C)(C)C)OP(N(C(C)C)C(C)C)OCCC#N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Related products
Frequently asked questions
Can the package size for N2-Isobutyryl-5'-O-DMTr-3'-O-TBDMS-guanosine-2'-CE phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-3OTP-0003 and CAS 1445905-51-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 3'-O-TBDMS Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.