Amino-modified Nucleosides
4-Amino-5-iodo-7-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine
Quick view. A stereodefined 3-deoxy-3-fluoro beta-D nucleoside of a 4-amino-5-iodo pyrrolo[2,3-d]pyrimidine base. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
![Chemical structure of 4-Amino-5-iodo-7-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine](/structures/73d219745f52f2f7.svg)
Product profile
4-Amino-5-iodo-7-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine is classified as 3-deoxy-3-fluoro 4-amino-5-iodo pyrrolopyrimidine nucleoside (Formula C11H12FIN4O3; molecular weight 394.14 g/mol).
4-Amino-5-iodo-7-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 4-Amino-5-iodo-7-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Useful catalog search terms
- XMTIATHWOKECGD-IOSLPCCCSA-N
Physicochemical data
| PubChem CID | 164613863 |
|---|---|
| IUPAC name | (2R,3S,4S,5R)-2-(4-amino-5-iodopyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-5-(hydroxymethyl)oxolan-3-ol |
| InChIKey | XMTIATHWOKECGD-IOSLPCCCSA-N |
| InChI | InChI=1S/C11H12FIN4O3/c12-7-5(2-18)20-11(8(7)19)17-1-4(13)6-9(14)15-3-16-10(6)17/h1,3,5,7-8,11,18-19H,2H2,(H2,14,15,16)/t5-,7-,8-,11-/m1/s1 |
| SMILES | C1=C(C2=C(N=CN=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)F)O)N)I |
| Canonical SMILES | C1=C(C2=C(N=CN=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)F)O)N)I |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 4-Amino-5-iodo-7-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 4-Amino-5-iodo-7-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0080, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.