Amino-modified Nucleosides
4-Amino-6-bromo-5-cyano-1-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine
Quick view. A stereodefined 3-deoxy-3-fluoro beta-D nucleoside bearing a 4-amino-6-bromo-5-cyano pyrrolopyrimidine base. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
![Chemical structure of 4-Amino-6-bromo-5-cyano-1-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine](/structures/142bfbcbbaed759a.svg)
Product profile
4-Amino-6-bromo-5-cyano-1-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine is classified as 3-deoxy-3-fluoro 4-amino-6-bromo-5-cyano pyrrolopyrimidine nucleoside (Formula C12H11BrFN5O3; molecular weight 372.15 g/mol).
4-Amino-6-bromo-5-cyano-1-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 4-Amino-6-bromo-5-cyano-1-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Useful catalog search terms
- ZRJHCXSMWVSRMH-JTFADIMSSA-N
Physicochemical data
| PubChem CID | 177700409 |
|---|---|
| IUPAC name | 6-bromo-1-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-imino-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile |
| InChIKey | ZRJHCXSMWVSRMH-JTFADIMSSA-N |
| InChI | InChI=1S/C12H11BrFN5O3/c13-9-4(1-15)6-10(16)17-3-19(11(6)18-9)12-8(21)7(14)5(2-20)22-12/h3,5,7-8,12,16,18,20-21H,2H2/t5-,7-,8-,12-/m1/s1 |
| SMILES | C1=NC(=N)C2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)F)O)NC(=C2C#N)Br |
| Canonical SMILES | C1=NC(=N)C2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)F)O)NC(=C2C#N)Br |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 4-Amino-6-bromo-5-cyano-1-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 4-Amino-6-bromo-5-cyano-1-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0082, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.