Amino-modified Nucleosides
5-[3-[[6-(Trifluoroacetamido)hexyl]amino]-3-oxoprop-1-en-1-yl]-5'-O-DMTr-2'-deoxyuridine
Quick view. A 5'-O-DMTr-protected 2'-deoxyuridine bearing a C5 propenamide-linked 6-trifluoroacetamidohexyl chain; alkene geometry is unspecified. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
![Chemical structure of 5-[3-[[6-(Trifluoroacetamido)hexyl]amino]-3-oxoprop-1-en-1-yl]-5'-O-DMTr-2'-deoxyuridine](/structures/75be7e0d8902abc6.svg)
Product profile
5-[3-[[6-(Trifluoroacetamido)hexyl]amino]-3-oxoprop-1-en-1-yl]-5'-O-DMTr-2'-deoxyuridine is classified as 5'-o-dmtr-protected c5-(trifluoroacetamidohexyl)-propenamide 2'-deoxyuridine (Formula C41H45F3N4O9; molecular weight 794.82 g/mol).
5-[3-[[6-(Trifluoroacetamido)hexyl]amino]-3-oxoprop-1-en-1-yl]-5'-O-DMTr-2'-deoxyuridine provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 5-[3-[[6-(Trifluoroacetamido)hexyl]amino]-3-oxoprop-1-en-1-yl]-5'-O-DMTr-2'-deoxyuridine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- 5-[3-[(6-TFA-Aminohexyl)amino]-3-oxo-propen-1-yl]-5'-O-DMTr-2'-deoxyuridine
- 5-[3-[(6-TFA-Aminohexyl)amino]-3-oxo-propen-1-yl]-5'-O-DMT-2'-deoxyuridine
Useful catalog search terms
- FHJKJNOZOPKQQQ-GABYNLOESA-N
Physicochemical data
| InChIKey | FHJKJNOZOPKQQQ-GABYNLOESA-N |
|---|---|
| Terminal amino protection | Trifluoroacetamide |
| Alkene geometry | Unspecified |
| InChI | InChI=1S/C41H45F3N4O9/c1-54-31-17-13-29(14-18-31)40(28-10-6-5-7-11-28,30-15-19-32(55-2)20-16-30)56-26-34-33(49)24-36(57-34)48-25-27(37(51)47-39(48)53)12-21-35(50)45-22-8-3-4-9-23-46-38(52)41(42,43)44/h5-7,10-21,25,33-34,36,49H,3-4,8-9,22-24,26H2,1-2H3,(H,45,50)(H,46,52)(H,47,51,53)/t33-,34+,36+/m0/s1 |
| SMILES | COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H](C[C@@H](O4)N5C=C(C(=O)NC5=O)C=CC(=O)NCCCCCCNC(=O)C(F)(F)F)O |
| Canonical SMILES | COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H](C[C@@H](O4)N5C=C(C(=O)NC5=O)C=CC(=O)NCCCCCCNC(=O)C(F)(F)F)O |
| PubChem CID | 131876674 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 5-[3-[[6-(Trifluoroacetamido)hexyl]amino]-3-oxoprop-1-en-1-yl]-5'-O-DMTr-2'-deoxyuridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5-[3-[[6-(Trifluoroacetamido)hexyl]amino]-3-oxoprop-1-en-1-yl]-5'-O-DMTr-2'-deoxyuridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0087, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.