Modified Nucleosides
5,6-Dihydrouridine
Quick view. We supply 5,6-Dihydrouridine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 5627-05-4. Catalog target purity: Specification on request.
Product profile
5,6-Dihydrouridine is classified as nucleoside or protected nucleoside intermediate (Formula C9H14N2O6; molecular weight 246.22).
5,6-Dihydrouridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5,6-Dihydrouridine, reported solubility: DMF: 16 mg/ml; DMSO: 10 mg/ml; PBS (pH 7.2): 5 mg/ml. Storage: Store at -20°C.
Names and search terms
Confirmed or normalized name variants
- dihydrouridine
- Uridine, 5,6-dihydro-
- 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one
Useful catalog search terms
- CAS 5627-05-4
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C9H14N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h4,6-8,12,14-15H,1-3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s |
|---|---|
| InChIKey | ZPTBLXKRQACLCR-XVFCMESISA-N |
| SMILES | C1CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O |
| Density | 1.614±0.06 g/cm3(Predicted) |
| pKa | 12.40±0.20(Predicted) |
| Form | A crystalline solid |
| Color | White to off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 5,6-Dihydrouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0587 and CAS 5627-05-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.