2'-O-Me Nucleosides
5'-Amino-5'-deoxy-2'-O-methyl-5-methyluridine
Quick view. 2'-O-Methyluridine derivative bearing a 5'-amino group and a 5-methyl substituent on the pyrimidine base. CAS 251296-69-2. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5'-Amino-5'-deoxy-2'-O-methyl-5-methyluridine is classified as 2'-o-me nucleosides (Formula C11H17N3O5; molecular weight 271.27 g/mol).
5'-Amino-5'-deoxy-2'-O-methyl-5-methyluridine provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 5'-Amino-5'-deoxy-2'-O-methyl-5-methyluridine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Useful catalog search terms
- 251296-69-2
Physicochemical data
| PubChem CID | 10778510 |
|---|---|
| Systematic name | 1-[(2R,3R,4R,5R)-5-(aminomethyl)-4-hydroxy-3-methoxyoxolan-2-yl]-5-methylpyrimidine-2,4-dione |
| Chemical form | Neutral 5'-amino-5'-deoxy-2'-O-methyl-5-methyluridine nucleoside |
| Stereochemical scope | Ribofuranose stereocenters encoded as (2R,3R,4R,5R) |
| InChIKey | PODAXORFJMIGLN-FDDDBJFASA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 5'-Amino-5'-deoxy-2'-O-methyl-5-methyluridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5'-Amino-5'-deoxy-2'-O-methyl-5-methyluridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2OMN-0071 and CAS 251296-69-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-O-Me Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.