Amino-modified Nucleosides
5'-Amino-5'-deoxyguanosine
Quick view. A guanosine derivative in which the 5'-hydroxymethyl group is replaced by an aminomethyl group. CAS 4099-84-7. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5'-Amino-5'-deoxyguanosine is classified as amino-modified nucleosides (Formula C10H14N6O4; molecular weight 282.26).
5'-Amino-5'-deoxyguanosine — Used as a 5'-terminal amino modification in chemically synthesized RNA oligomers.
For 5'-Amino-5'-deoxyguanosine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- Guanosine, 5'-amino-5'-deoxy-
- 5'-NH2-Guo
- NSC 108608
Useful catalog search terms
- CAS 4099-84-7
Physicochemical data
| Systematic name | 2-amino-9-[(2R,3R,4S,5R)-5-(aminomethyl)-3,4-dihydroxyoxolan-2-yl]-3H-purin-6-one |
|---|---|
| 5'-substitution | 5'-amino-5'-deoxy |
| PubChem CID | 135475611 |
| InChI | InChI=1S/C10H14N6O4/c11-1-3-5(17)6(18)9(20-3)16-2-13-4-7(16)14-10(12)15-8(4)19/h2-3,5-6,9,17-18H,1,11H2,(H3,12,14,15,19)/t3-,5-,6-,9-/m1/s1 |
| InChIKey | JUWYSPSHBRXOGR-UUOKFMHZSA-N |
| SMILES | C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)CN)O)O)N=C(NC2=O)N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 5'-Amino-5'-deoxyguanosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5'-Amino-5'-deoxyguanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0093 and CAS 4099-84-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not a BX Lab lot specification or product-performance claim.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.