Amino-modified Nucleosides
5'-Amino-5'-deoxythymidine
Quick view. Thymidine nucleoside in which the 5'-hydroxyl is replaced by an amino group. CAS 25152-20-9. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5'-Amino-5'-deoxythymidine is classified as amino-modified nucleosides (Formula C10H15N3O4; molecular weight 241.24 g/mol).
5'-Amino-5'-deoxythymidine provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 5'-Amino-5'-deoxythymidine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- Thymidine, 5'-amino-5'-deoxy-
Useful catalog search terms
- 25152-20-9
Physicochemical data
| PubChem CID | 65311 |
|---|---|
| Systematic name | 1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxyoxolan-2-yl]-5-methylpyrimidine-2,4-dione |
| Chemical form | Neutral 5'-amino-5'-deoxythymidine nucleoside |
| Stereochemical scope | Deoxyribose stereocenters encoded as (2R,4S,5R) |
| InChIKey | PYWLBQPICCQJFF-XLPZGREQSA-N |
| InChI | InChI=1S/C10H15N3O4/c1-5-4-13(10(16)12-9(5)15)8-2-6(14)7(3-11)17-8/h4,6-8,14H,2-3,11H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s1 |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CN)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 5'-Amino-5'-deoxythymidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5'-Amino-5'-deoxythymidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0063 and CAS 25152-20-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.