Amino-modified Nucleosides
5-Aminomethyl-2',3'-O-isopropylidene-2-thiouridine
Quick view. A 5-aminomethyl-2-thiouridine derivative bearing a cyclic 2',3'-O-isopropylidene group, CAS 1428903-07-4. CAS 1428903-07-4. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5-Aminomethyl-2',3'-O-isopropylidene-2-thiouridine is classified as amino-modified nucleosides (Formula C13H19N3O5S; molecular weight 329.37).
5-Aminomethyl-2',3'-O-isopropylidene-2-thiouridine — A protected 5-aminomethyl-2-thiouridine intermediate for research use in modified nucleoside synthesis.
For 5-Aminomethyl-2',3'-O-isopropylidene-2-thiouridine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- 5-Aminomethyl-2',3'-di-O-isopropylidene 2-thiouridine
- TNU1409
Useful catalog search terms
- 5-(Aminomethyl)-2',3'-O-isopropylidene-2-thiouridine
- 1428903-07-4
Physicochemical data
| SMILES | CC1(O[C@@H]2[C@H](O[C@H]([C@@H]2O1)N3C=C(C(=O)NC3=S)CN)CO)C |
|---|---|
| Nucleoside core | 2-Thiouridine |
| Amino modification | 5-Aminomethyl |
| Sugar protection | Cyclic 2',3'-O-isopropylidene |
| Hydroxyl state | Free 5'-OH |
| PubChem CID | 168449032 |
| InChIKey | LLYVIOOQSMCMDM-TURQNECASA-N |
| InChI | InChI=1S/C13H19N3O5S/c1-13(2)20-8-7(5-17)19-11(9(8)21-13)16-4-6(3-14)10(18)15-12(16)22/h4,7-9,11,17H,3,5,14H2,1-2H3,(H,15,18,22)/t7-,8-,9-,11-/m1/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 5-Aminomethyl-2',3'-O-isopropylidene-2-thiouridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
3'-NH₂-ddA
Amino-modified Nucleosides · CAS: 7403-25-0
BX-MN-00073'-NH₂-ddC
Amino-modified Nucleosides · CAS: 84472-90-2
BX-MN-00083'-NH₂-ddG
Amino-modified Nucleosides · CAS: 66323-49-7
BX-MN-01762-Aminoadenosine
Amino-modified Nucleosides · CAS: 2096-10-8
BX-AMN-01343'-beta-Azido-2',3'-dideoxyuridine
Amino-modified Nucleosides · CAS: 101039-96-7
BX-AMN-00072-Amino-2',3'-dideoxyadenosine
Amino-modified Nucleosides · CAS: 107550-73-2
Frequently asked questions
Can the package size for 5-Aminomethyl-2',3'-O-isopropylidene-2-thiouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0023 and CAS 1428903-07-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.