2'-O-Me Nucleosides
N-Benzyl-2'-O-methyluridine-5-carboxamide
Quick view. A 2'-O-methyluridine nucleoside bearing an N-benzyl carboxamide at base C5. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
N-Benzyl-2'-O-methyluridine-5-carboxamide is classified as c5 n-benzyl carboxamide-substituted 2'-o-methyluridine (Formula C18H21N3O7; molecular weight 391.38 g/mol).
N-Benzyl-2'-O-methyluridine-5-carboxamide supports modified RNA/antisense designs where methylated ribose positions are used to improve stability or reduce unwanted immune stimulation.
For N-Benzyl-2'-O-methyluridine-5-carboxamide, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- 5-[(benzylamino) carbonyl]-2'-O-methyl-uridine
Useful catalog search terms
- HSVRHYDSGNWNGH-VMUDFCTBSA-N
Physicochemical data
| InChIKey | HSVRHYDSGNWNGH-VMUDFCTBSA-N |
|---|---|
| InChI | InChI=1S/C18H21N3O7/c1-27-14-13(23)12(9-22)28-17(14)21-8-11(16(25)20-18(21)26)15(24)19-7-10-5-3-2-4-6-10/h2-6,8,12-14,17,22-23H,7,9H2,1H3,(H,19,24)(H,20,25,26)/t12-,13-,14-,17-/m1/s1 |
| SMILES | CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)C(=O)NCC3=CC=CC=C3)CO)O |
| Canonical SMILES | CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)C(=O)NCC3=CC=CC=C3)CO)O |
| PubChem CID | 127258198 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe N-Benzyl-2'-O-methyluridine-5-carboxamide or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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BX-2OMN-0004N6,2'-O-Dimethyladenosine
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BX-2OMN-00052'-O-Methylinosine
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BX-MN-01752'-O-Methylcytidine
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2'-O-Me Nucleosides · CAS: 2140-71-8
Frequently asked questions
Can the package size for N-Benzyl-2'-O-methyluridine-5-carboxamide be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2OMN-0093, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-O-Me Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.