Amino-modified Nucleosides
5-Benzylaminocarbonyl-2'-O-methyluridine
Quick view. A 2'-O-methyluridine building block bearing a 5-benzylaminocarbonyl substituent for structure-specific nucleoside and nucleotide synthesis research. CAS 1648558-95-5. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5-Benzylaminocarbonyl-2'-O-methyluridine is classified as amino-modified nucleosides (Formula C18H21N3O7; molecular weight 391.38).
5-Benzylaminocarbonyl-2'-O-methyluridine — Modified uridine building block for structure-specific nucleoside and nucleotide synthesis research.
For 5-Benzylaminocarbonyl-2'-O-methyluridine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Useful catalog search terms
- CAS 1648558-95-5
- 5-benzylaminocarbonyl 2-O-methyluridine
Physicochemical data
| Nucleoside modification | 2'-O-methyl |
|---|---|
| 5-position substituent | Benzylaminocarbonyl |
| PubChem CID | 127258198 |
| InChI | InChI=1S/C18H21N3O7/c1-27-14-13(23)12(9-22)28-17(14)21-8-11(16(25)20-18(21)26)15(24)19-7-10-5-3-2-4-6-10/h2-6,8,12-14,17,22-23H,7,9H2,1H3,(H,19,24)(H,20,25,26)/t12-,13-,14-,17-/m1/s1 |
| InChIKey | HSVRHYDSGNWNGH-VMUDFCTBSA-N |
| SMILES | CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cc(C(=O)NCc2ccccc2)c(=O)[nH]c1=O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 5-Benzylaminocarbonyl-2'-O-methyluridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5-Benzylaminocarbonyl-2'-O-methyluridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0149 and CAS 1648558-95-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.