2'-O-Me Nucleosides
5-(Furan-2-yl)-2'-O-methyl-5'-O-DMTr-uridine
Quick view. Protected 2'-O-methyl uridine derivative bearing a 5-(furan-2-yl) substituent and a 5'-O-dimethoxytrityl group. CAS 2095417-47-1. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5-(Furan-2-yl)-2'-O-methyl-5'-O-DMTr-uridine is classified as 2'-o-me nucleosides (Formula C35H34N2O9; molecular weight 626.66 g/mol).
5-(Furan-2-yl)-2'-O-methyl-5'-O-DMTr-uridine supports modified RNA/antisense designs where methylated ribose positions are used to improve stability or reduce unwanted immune stimulation.
For 5-(Furan-2-yl)-2'-O-methyl-5'-O-DMTr-uridine, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- 5-Furan-2-yl-2'-O-methyl-5'-O-DMT-uridine
Useful catalog search terms
- 2095417-47-1
Physicochemical data
| Base scaffold | Uridine |
|---|---|
| Base modification | 5-(furan-2-yl) |
| Sugar modification | 2'-O-methyl |
| 5' protection | O-DMTr |
| InChIKey | HTMVCWPFTLMWRP-WTGZKXAYSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 5-(Furan-2-yl)-2'-O-methyl-5'-O-DMTr-uridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
2-Amino-2'-O-methyladenosine
2'-O-Me Nucleosides · CAS: 80791-87-3
BX-2OMN-00032'-O-Methyl-7-deazaadenosine
2'-O-Me Nucleosides · CAS: 68345-70-0
BX-2OMN-0004N6,2'-O-Dimethyladenosine
2'-O-Me Nucleosides · CAS: 57817-83-1
BX-2OMN-00052'-O-Methylinosine
2'-O-Me Nucleosides · CAS: 3881-21-8
BX-MN-01752'-O-Methylcytidine
2'-O-Me Nucleosides · CAS: 2140-72-9
BX-MN-01782'-O-Methylguanosine
2'-O-Me Nucleosides · CAS: 2140-71-8
Frequently asked questions
Can the package size for 5-(Furan-2-yl)-2'-O-methyl-5'-O-DMTr-uridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2OMN-0051 and CAS 2095417-47-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-O-Me Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.