Modified Nucleosides
5-Hydroxymethyl-2',3'-O-isopropylidene-2-thiouridine
Quick view. A 5-hydroxymethyl-2-thiouridine derivative in which the 2' and 3' hydroxyl groups are protected as a single isopropylidene acetal. CAS 58479-71-3. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5-Hydroxymethyl-2',3'-O-isopropylidene-2-thiouridine is classified as acetonide-protected 2-thiouridine derivative (Formula C13H18N2O6S; molecular weight 330.36 g/mol).
5-Hydroxymethyl-2',3'-O-isopropylidene-2-thiouridine is associated with uridine-containing substrates for U-position incorporation in RNA or modified RNA studies.
For 5-Hydroxymethyl-2',3'-O-isopropylidene-2-thiouridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2'-O,3'-O-Isopropylidene-5-(hydroxymethyl)-2-thiouridine
Useful catalog search terms
- 58479-71-3
- MFCD25542462
Physicochemical data
| Protecting group | 2',3'-O-isopropylidene |
|---|---|
| MDL number | MFCD25542462 |
| PubChem CID | 53678259 |
| InChI | InChI=1S/C13H18N2O6S/c1-13(2)20-8-7(5-17)19-11(9(8)21-13)15-3-6(4-16)10(18)14-12(15)22/h3,7-9,11,16-17H,4-5H2,1-2H3,(H,14,18,22)/t7-,8-,9-,11-/m1/s1 |
| InChIKey | BETDENPMPLSMTA-TURQNECASA-N |
| SMILES | CC1(O[C@@H]2[C@H](O[C@H]([C@@H]2O1)N3C=C(C(=O)NC3=S)CO)CO)C |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Frequently asked questions
Can the package size for 5-Hydroxymethyl-2',3'-O-isopropylidene-2-thiouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0599 and CAS 58479-71-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
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