Halogenated Nucleosides
2',3'-Dideoxy-5-iodocytidine
Quick view. 2',3'-Dideoxy-5-iodocytidine is a dideoxycytidine nucleoside bearing iodine at pyrimidine C5, with CAS 114748-57-1. CAS 114748-57-1. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2',3'-Dideoxy-5-iodocytidine is classified as 5-iodo-2',3'-dideoxycytidine nucleoside (Formula C9H12IN3O3; molecular weight 337.11).
2',3'-Dideoxy-5-iodocytidine can be evaluated in chain-termination, sequencing-control or polymerase-specific substrate studies.
For 2',3'-Dideoxy-5-iodocytidine, polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
Names and search terms
Confirmed or normalized name variants
- 5-Iodo-2',3'-dideoxycytidine
- Cytidine, 2',3'-dideoxy-5-iodo-
- PubChem CID 14630104
Useful catalog search terms
- CAS 114748-57-1
Physicochemical data
| IUPAC name | 4-amino-1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one |
|---|---|
| InChI | InChI=1S/C9H12IN3O3/c10-6-3-13(9(15)12-8(6)11)7-2-1-5(4-14)16-7/h3,5,7,14H,1-2,4H2,(H2,11,12,15)/t5-,7+/m0/s1 |
| InChIKey | AMWJPSDPTPKJGN-CAHLUQPWSA-N |
| SMILES | C1C[C@@H](O[C@@H]1CO)N2C=C(C(=NC2=O)N)I |
| Structural feature | Pyrimidine C5 iodine with 2',3'-dideoxy sugar |
| PubChem CID | 14630104 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 2',3'-Dideoxy-5-iodocytidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2',3'-Dideoxy-5-iodocytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0014 and CAS 114748-57-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.