Halogenated Nucleosides
5-Iodouridine
Quick view. We supply 5-Iodouridine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 1024-99-3. Catalog target purity: Specification on request.
Product profile
5-Iodouridine is classified as nucleoside or protected nucleoside intermediate (Formula C9H11IN2O6; molecular weight 370.1).
5-Iodouridine has shown to enhance the effect of gamma irradiation in hamster cells. It is used as catalytic agent, petrochemical additive, used in organic synthesis.
For 5-Iodouridine, reported solubility: Acetonitrile: Slightly soluble Methanol: Soluble Water: Slightly soluble. Storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- 2,4-DIHYDROXY-5-IODO-1-BETA-D-RIBOFURANOSYLPYRIMIDINE
- 5-IODO-1-(BETA-D-RIBOFURANOSYL)URACIL
- 2,4-dihydroxy-5-iodo-1-β-d-ribofuranosylpyrimidine
- 5-Iodo-D-uridine
- 1-(β-D-Ribofuranosyl)-2-hydroxy-5-iodopyrimidine-4(1H)-one
- 1-β-D-Ribofuranosyl-2-hydroxy-5-iodo-1,4-dihydropyrimidine-4-one
Useful catalog search terms
- CAS 1024-99-3
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| InChI | InChI=1S/C9H11IN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s |
|---|---|
| InChIKey | RKSLVDIXBGWPIS-UAKXSSHOSA-N |
| SMILES | OC[C@H]1O[C@@H](N2C=C(I)C(=O)NC2=O)[C@H](O)[C@@H]1O |
| Melting point | 205-207 °C (dec.) (lit.) |
| Density | 2.27±0.1 g/cm3(Predicted) |
| pKa | 7.94±0.10(Predicted) |
| Form | Powder |
| Color | White |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 5-Iodouridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 5-Iodouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0006 and CAS 1024-99-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.