Modified Nucleosides
5-Methyl-4-thiouridine
Quick view. A stereodefined uridine nucleoside bearing methyl at base C5 and sulfur at base C4. CAS 49555-43-3. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5-Methyl-4-thiouridine is classified as c5-methyl c4-thio uridine nucleoside (Formula C10H14N2O5S; molecular weight 274.30 g/mol).
5-Methyl-4-thiouridine is associated with uridine-containing substrates for U-position incorporation in RNA or modified RNA studies.
For 5-Methyl-4-thiouridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Useful catalog search terms
- 49555-43-3
- IXDWFVOGUMAKFI-JXOAFFINSA-N
Physicochemical data
| PubChem CID | 56613468 |
|---|---|
| IUPAC name | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-4-sulfanylidenepyrimidin-2-one |
| InChIKey | IXDWFVOGUMAKFI-JXOAFFINSA-N |
| InChI | InChI=1S/C10H14N2O5S/c1-4-2-12(10(16)11-8(4)18)9-7(15)6(14)5(3-13)17-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,18)/t5-,6-,7-,9-/m1/s1 |
| SMILES | CC1=CN(C(=O)NC1=S)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Frequently asked questions
Can the package size for 5-Methyl-4-thiouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0553 and CAS 49555-43-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
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