Amino-modified Nucleosides
5-(Methylaminomethyl)-2-thiouridine
Quick view. A uridine nucleoside bearing a methylaminomethyl substituent at pyrimidine C5 and a thioxo group at C2. CAS 32860-54-1. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5-(Methylaminomethyl)-2-thiouridine is classified as c5-methylaminomethyl-2-thioxo uridine nucleoside (Formula C11H17N3O5S; molecular weight 303.34 g/mol).
5-(Methylaminomethyl)-2-thiouridine provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 5-(Methylaminomethyl)-2-thiouridine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Useful catalog search terms
- 32860-54-1
- HXVKEKIORVUWDR-FDDDBJFASA-N
Physicochemical data
| PubChem CID | 3036488 |
|---|---|
| IUPAC name | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(methylaminomethyl)-2-sulfanylidenepyrimidin-4-one |
| InChIKey | HXVKEKIORVUWDR-FDDDBJFASA-N |
| InChI | InChI=1S/C11H17N3O5S/c1-12-2-5-3-14(11(20)13-9(5)18)10-8(17)7(16)6(4-15)19-10/h3,6-8,10,12,15-17H,2,4H2,1H3,(H,13,18,20)/t6-,7-,8-,10-/m1/s1 |
| SMILES | CNCc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=S)nc1O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 5-(Methylaminomethyl)-2-thiouridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5-(Methylaminomethyl)-2-thiouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0071 and CAS 32860-54-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.