Amino-modified Nucleosides
5-N-(tert-Butoxycarbonylmethyl)-N-trifluoroacetyl-aminomethyl-2'-O-methyluridine
Quick view. 5-N-(tert-Butoxycarbonylmethyl)-N-trifluoroacetyl-aminomethyl-2'-O-methyluridine is listed for research-use inquiry under Amino-modified Nucleosides. Its identity is controlled by the retained exact structure and product-form evidence because no public CAS Registry Number is assigned. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5-N-(tert-Butoxycarbonylmethyl)-N-trifluoroacetyl-aminomethyl-2'-O-methyluridine is classified as amino-modified nucleosides (Formula C19H26F3N3O9; molecular weight 497.42).
5-N-(tert-Butoxycarbonylmethyl)-N-trifluoroacetyl-aminomethyl-2'-O-methyluridine provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 5-N-(tert-Butoxycarbonylmethyl)-N-trifluoroacetyl-aminomethyl-2'-O-methyluridine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Physicochemical data
| CAS status | No public CAS assigned |
|---|---|
| Identity control | Reviewed exact name, structure, and product form |
| Covalent InChIKey | HRNJSEZTVMMKFO-BPGGGUHBSA-N |
| Covalent InChI | InChI=1S/C19H26F3N3O9/c1-18(2,3)34-11(27)7-24(16(30)19(20,21)22)5-9-6-25(17(31)23-14(9)29)15-13(32-4)12(28)10(8-26)33-15/h6,10,12-13,15,26,28H,5,7-8H2,1-4H3,(H,23,29,31)/t10-,12-,13-,15-/m1/s1 |
| Covalent SMILES | CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cc(CN(CC(=O)OC(C)(C)C)C(=O)C(F)(F)F)c(=O)[nH]c1=O |
| Canonical covalent SMILES | CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cc(CN(CC(=O)OC(C)(C)C)C(=O)C(F)(F)F)c(=O)[nH]c1=O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 5-N-(tert-Butoxycarbonylmethyl)-N-trifluoroacetyl-aminomethyl-2'-O-methyluridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
3'-NH₂-ddA
Amino-modified Nucleosides · CAS: 7403-25-0
BX-MN-00073'-NH₂-ddC
Amino-modified Nucleosides · CAS: 84472-90-2
BX-MN-00083'-NH₂-ddG
Amino-modified Nucleosides · CAS: 66323-49-7
BX-MN-01762-Aminoadenosine
Amino-modified Nucleosides · CAS: 2096-10-8
BX-AMN-01343'-beta-Azido-2',3'-dideoxyuridine
Amino-modified Nucleosides · CAS: 101039-96-7
BX-AMN-00072-Amino-2',3'-dideoxyadenosine
Amino-modified Nucleosides · CAS: 107550-73-2
Frequently asked questions
Can the package size for 5-N-(tert-Butoxycarbonylmethyl)-N-trifluoroacetyl-aminomethyl-2'-O-methyluridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0216, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.