Amino-modified Nucleosides
5-[(2-Naphthalenylmethyl)aminocarbonyl]-2'-O-methyluridine
Quick view. A 2'-O-methyluridine building block bearing a 5-[(2-naphthalenylmethyl)aminocarbonyl] substituent for structure-specific synthesis research. CAS 1675178-56-9. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
![Chemical structure of 5-[(2-Naphthalenylmethyl)aminocarbonyl]-2'-O-methyluridine](/structures/ba6804b2eda75bb8.svg)
Product profile
5-[(2-Naphthalenylmethyl)aminocarbonyl]-2'-O-methyluridine is classified as amino-modified nucleosides (Formula C22H23N3O7; molecular weight 441.43).
5-[(2-Naphthalenylmethyl)aminocarbonyl]-2'-O-methyluridine — 5-Carboxamide-functionalized 2'-O-methyluridine building block for structure-specific modified-nucleoside and nucleotide synthesis research.
For 5-[(2-Naphthalenylmethyl)aminocarbonyl]-2'-O-methyluridine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- Uridine, 2'-O-methyl-5-[[(2-naphthalenylmethyl)amino]carbonyl]-
Useful catalog search terms
- CAS 1675178-56-9
- 2-naphthalenylmethyl aminocarbonyl uridine
Physicochemical data
| Nucleoside modification | 2'-O-methyluridine |
|---|---|
| 5-position substituent | [(2-Naphthalenylmethyl)amino]carbonyl |
| PubChem CID | 165353054 |
| InChI | InChI=1S/C22H23N3O7/c1-31-18-17(27)16(11-26)32-21(18)25-10-15(20(29)24-22(25)30)19(28)23-9-12-6-7-13-4-2-3-5-14(13)8-12/h2-8,10,16-18,21,26-27H,9,11H2,1H3,(H,23,28)(H,24,29,30)/t16-,17-,18-,21-/m1/s1 |
| InChIKey | GDRHQLOQYOBSAI-NEYJZJCJSA-N |
| SMILES | CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cc(C(=O)NCc2ccc3ccccc3c2)c(=O)[nH]c1=O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 5-[(2-Naphthalenylmethyl)aminocarbonyl]-2'-O-methyluridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5-[(2-Naphthalenylmethyl)aminocarbonyl]-2'-O-methyluridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0150 and CAS 1675178-56-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.