Amino-modified Nucleosides
5-(Naphthalen-2-ylmethylcarbamoyl)-3'-O-acetyl-2'-O-methyl-5'-O-DMTr-uridine
Quick view. Protected uridine derivative bearing a 5-(naphthalen-2-ylmethylcarbamoyl) group, 3'-O-acetyl, 2'-O-methyl, and 5'-O-DMTr substitutions. CAS 2095417-00-6. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5-(Naphthalen-2-ylmethylcarbamoyl)-3'-O-acetyl-2'-O-methyl-5'-O-DMTr-uridine is classified as amino-modified nucleosides (Formula C45H43N3O10; molecular weight 785.85 g/mol).
5-(Naphthalen-2-ylmethylcarbamoyl)-3'-O-acetyl-2'-O-methyl-5'-O-DMTr-uridine provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 5-(Naphthalen-2-ylmethylcarbamoyl)-3'-O-acetyl-2'-O-methyl-5'-O-DMTr-uridine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Useful catalog search terms
- 2095417-00-6
Physicochemical data
| Nucleoside scaffold | uridine |
|---|---|
| C5 substituent | naphthalen-2-ylmethylcarbamoyl |
| Sugar protection | 3'-O-acetyl and 5'-O-DMTr |
| Sugar modification | 2'-O-methyl |
| InChIKey | YLJAEVQTZVZLDY-OYSHXDRRSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 5-(Naphthalen-2-ylmethylcarbamoyl)-3'-O-acetyl-2'-O-methyl-5'-O-DMTr-uridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5-(Naphthalen-2-ylmethylcarbamoyl)-3'-O-acetyl-2'-O-methyl-5'-O-DMTr-uridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0047 and CAS 2095417-00-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.